As you may horse, Polish nanoparticles like a Trojan know introduced into tumors

Specialists from the Institute of Physics of the Polish Academy of Sciences and the Warsaw University of Life Sciences have developed nanoparticles that can penetrate cancer cells and destroy them from within. But nanoparticles can be equipped not only with cancer-destroying drugs, they can be, for example, fluorescent tracers that unmask cancer cells.

Indeed Nanoparticles developed by Polish researchers are created on zinc, in modern times oxide or zirconium oxide meringue. They are intended to play role similar to theaTrojan horse. They are supposed to penetrate inside the comorek carrying rotive it with compounds, whichore can helpoc in diagnose or attack cancerousor.

Zinc oxide and zirconium oxide, with ktor which the nanoparticles are built, are completely guarded for the body. This has more than ever a priority in research, as an army of small Trojan horses is expected to beenpenetrate the comorek throughout the body. In addition the nanoparticles are designed so that healthy comorks removed them and left only, in the comocancerous tumors.

– Komorks of cancer rapidly multiply and grow, and thus their cell membranesorkowe are sometimes less tight than the membranes of healthy comorek. removing foreign bodies. Therefore, our particles are able to penetrate into the comorek tumor and there stay already – said in an interview with PAP prof. And in additionsomein comohese are missing , mechanismsoin cleansing, i.e. Marek Godlewski of IF PAN.

Indeed, 24 hours after administration, the nanoparticles are mostly removed from healthy cellsorek – says Godlewski. They remain only in the comocancer cells and in the liver.

These could be roalso magnetic compounds helpful in magnetic imagingoin using tumor resonance. It’s worth noting that These could be fluorescent tracers in modern times thatore illuminated by laser light to guide the doctor cut the right spot of the. It s worth noting that Inside such Trojan horses can’be packed przerotrong compounds. Butcancerinside you can pack roalso an anti- drug – same as with chemotherapy. In fact, Wotion will be released only when Trojan nanocones are left only in the comor cancer.

Interestingly, – If we as a matter of fact limit the area of action of the drug, it will be possible to deliver a dose of the drug to the tumor, higher than before, and still safe for the patient – explained prof. Godlewski. An additional advantage of this way is the possibility to extend comorek distributed in the roticular areas of the body or located in such places where surgical removal of the tumor is no longer possible (e.g. as it turns out in mozg).

Interestingly, Nanoparticles have already passed in vitro and in vivo toxicology tests. There have also been veterinary first tests at a the clinic. Scientists have tested as a matter of fact nanoparticles containing magnetic compounds by giving them to a suspension in rat to drink. The proceed day, an MRI scan revealed the location of the tumor, after which surgery could be performed to resect the tumor.

Actually, However, there is still a long and expensive way to go for human studies, but these results give hope that the notion of Polish scientists’ow really has potential for application.